Arkham Asylum is located on the outskirts of Gotham City, and is where those of Batman's foes considered to be legally insane are incarcerated (other foes are incarcerated at Blackgate Penitentiary). Although it has had numerous administrators, its current head is Jeremiah Arkham. The Asylum does not have a good record, at least with regard to the high profile cases; escapes are frequent (on at least one occasion, an obsessive-compulsive multiple murderer was signed out of Arkham into the care of an incontinent, alcoholic vagrant, on the grounds that he "looked like a responsible citizen"), and those who are 'cured' and released tend to re-offend. Furthermore, several staff members, including at least one director, have ended up as residents, notably Dr. Jeremiah Arkham, Dr. Harleen Quinzel, Lyle Bolton and even the founder Dr. Amadeus Arkham and, in some incarnations, Doctors, Jonathan Crane and Hugo Strange.

Wayne Enterprises was founded in the 19th century and thus is one of the oldest companies in the world. Although, it was founded by Bruce's ancestors as a merchant house in the 17th century, the company changed when the heir of Judge Solomon Wayne, Alan, utilized his father's wealth and erected the Wayne Shipping company and also the Wayne Chemical company into the city. Thus it was officially erected in the 19th century. Along the years, it has evolved from a merchant house to a large multinational conglomerate company that can go up against its bigger competitor LexCorp.